publications
A list of all publications on Pubmed is available here.
Publications not on Pubmed
Some representative papers
Gulyani, A., Vitriol, E., Allen, R., Wu, J., Gremyachinskiy, D., Lewis, S., Dewar, B., Graves, L.M., Kay, B.K., Kuhlman, B., Elston T., and Hahn, K.M. A biosensor generated via high-throughput screening quantifies cell edge Src dynamics. Nature Chem Bio 7:437-444, 2011. PMC3135387. Online article.
Karginov, A.V., Zou, Y., Shirvanyants, D., Kota, P., Dokholyan, N.V., Young, D.D., Hahn, K.M*., and Deiters, A*. Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP. J Am Chem Soc, 133(3): 420-423, 2011. PMC3133816. Online article.
Karginov, A.V., Ding, F., Kota, P., Dokholyan, N.V., and Hahn, K.M. Engineered allosteric activation of kinases in living cells. Nature Biotech, July; 28(7): 743-7, 2010. PMC2902629. Online article.
Wu, Y, Frey, D., Lungu, O. I., Jaehrig, A., Schlichting, I., Kuhlman, B. and Hahn, K.M. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature, 461: 104-110, 2009. PMC2766670. Online article.
Machacek, M., Hodson, L., Welch, C., Elliot, H., Pertz, O., Nalbant, P., Abell, A., Johnson, G., Hahn, K.M.* and Danuser, G*. Coordination of Rho GTPase activities during cell protrusion. Nature, 461: 99-103, 2009. PMC2885353. Online article.Toutchkine, A., Nguyen, D.V., and Hahn, K.M. Merocyanine Dyes with Improved Photostability. Org. Lett. 9(15): 2775-2777, 2007. Online article.
Pertz, O., L. Hodgson, R. R. Klemke, and K.M. Hahn. Spatio-temporal dynamics of RhoA activity in migrating cells. Nature, 440(7087):1069-1072, 2006. Online article.
Subauste, M., O. Pertz, E. Adamson, C.E. Turner, S. Junger, K.M. Hahn. Vinculin Modulation of Paxillin-FAK Interactions Regulates ERK to Control Survival and Motility. J Cell Biol., 165:171-181, 2004. PMC2172187. Online article.
Nalbant, P., L. Hodgson, V. Kraynov, A. Toutchkine, K.M. Hahn. Activation of Endogenous Cdc42 Visualized in Living Cells. Science, 305: 1615-1619, 2004. Online article.Toutchkine, A., V. Kraynov, and K.M. Hahn. Solvent-Sensitive Dyes to Report Protein Conformational Changes in Living Cells. J. Amer. Chem. Soc., 125:4132-4145, 2003. Online article.
Kraynov, V. S., Chamberlain, C. E., Bokoch, G. M., Schwartz, M. A., Slabaugh, S., and K. M. Hahn. Localized Rac activation dynamics visualized in living cells. Science, 290: 333-337, 2000. Online article.
Bark, S. J., Schmid, S., and K. M. Hahn. A highly efficient method for site-specific modification of peptides after chemical synthesis. J. Am. Chem. Soc., 122 (15): 3567-3573, 2000. Online article.
Some recent papers from our collaborators, using our molecular imaging tools
Galic, M., Jeong, S., Tsai, F-C., Joubert, L-M., Wu, Y.I., Hahn, K.M., Cui, Y., and Meyer, T. External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane. Nature Cell Biol., 14(8):874-81, 2012. online article
Dietz, D.M., Sun, H., Lobo, M.K., Cahill, M.E., Chadwick, B., Gao, V., Koo, J.W., Mazei-Robison, M.S., Dias, C., Maze, I., Damez-Werno, D., Dietz, K.C., Scobie, K.N., Ferguson, D., Christoffel, D., Ohnishi, Y., Hodes, G.E., Zheng, Y., Neve, R.L., Hahn, K.M., Russo, S.J., and Nestler, E.J. Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons Nat Neurosci. Apr 22, 2012, doi: 10.1038/nn.3094. [Epub ahead of print] Online article.
Wang, X., He L, Wu, Y.I., Hahn, K.M., and Montell, D.J. Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol., 12(6): 591-7, 2011. PMC2929827. Online article.
Yoo, S.K., Deng, Q., Cavnar, P. J., Wu,Y.I., Hahn, K.M., Huttenlocher, A. Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish. Developmental Cell, 18(2): 226-236, 2010. PMC2824622. Online article.
Koivusalo, M., Welch, C., Hayashi, H., Scott, C.C., Kim, M., Alexander, T., Touret, N., Hahn, K.M., and Grinstein, S. Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signalling. J. Cell Biol., 188: 547-563, 2010. PMC2828922. Online article
Patents
US 6,951,947 (2005); US 7,176,037 (2007); US 7,351,797 (2008): US 7,592,188 (2009)