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RapR analogs of Src family kinases. Specific activation of the closely related family members Fyn, Src, and Lyn produce different cell phenotypes.

These 3 videos show:
top - Fyn (spreading);
middle - Src (spreading followed by movement);
bottom - Lyn (suprising kinked extensions).

by Pei Hsuan Chu
PNAS, 111(34):12420-25, 2014

~Updated 01/27/2022

© UNC Department of Pharmacology